Gorazd B. Stokin, MD, PhD (SI)

PROFESSIONAL BACKGROUND
2013 – present Chair of the International Clinical Research Center, Brno, Czech Republic
October 25, 2010 – 2013 Consultant Neurologist, Department of vascular neurology and neurological intensive therapy, Division of Neurology, University Medical Center, Ljubljana
July 6, 2010 – now Consultant Neurologist, Gerontopsychiatric Unit, University Psychiatric Hospital, Ljubljana
July 1, 2009 – December 31, 2009 Honorary Clinical Fellow and Visiting Scientist, Department of Clinical Neurosciences, Addenbrooke’s Hos­pital (Supervisor: P.J.Nestor) and Brain Repair Center, University of Cambridge (Group Leader: M.-G. Spillantini), Cambridge, UK
December 1, 2007 – June 29 2009 Senior Registrar in Neurology, Gerontopsychiatry Unit, University Psychiatric Hospital, Ljubljana
January 16, 2007 – May 25 2009 Dementia outpatient Clinical Fellow, Institute of Clinical Neurophysiology, Division of Neurology (Supervisor: D.B. Vodušek), University Medical Center, Ljubljana
January 14, 2008 – January 6, 2009 Chief Resident, Department of Neurology, Division of Neurology (Supervisor: Z. Pirtošek), University Medical Center, Ljubljana
November 2, 2004 – June 17 2010 Neurology Resident, Division of Neurology (Mentor: D.B. Vodušek), University Medical Center, Ljubljana
July 1, 2004 – October 29, 2004 Visiting Physician, Alzheimer’s Disease Research Center, Florence Riford Clinic (Mentor: L.J. Thal), Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, California, USA
July 1, 2003 – June 30, 2004 Postgraduate Researcher, Howard Hughes Medical Institute, George Palade Laboratories for Cellular and Molecular Medicine (Mentor: L.S.B.Goldstein), School of Medicine, University of California San Diego, La Jolla, California, USA
April 1, 1999 – June 30, 2003 Graduate Student Researcher, Howard Hughes Medical Institute, Cellular and Molecular Medicine West (Mentor: L.S.B. Goldstein), School of Medicine, University of California San Diego, La Jolla, California, USA
February 3, 1997 – March 31, 1999 Graduate Student Researcher, Department of Neurosciences, Cellular and Molecular Medicine East (Mentor: E.H. Koo), School of Medicine, University of California San Diego, La Jolla, California, USA
October 1, 1996 – January 31, 1997 Postgraduate Year-1 Resident then (from November 1)“Young Scientist” Graduate Researcher,De­partment of Endocrinology, Diabetes and Metabolic Disorders (Mentor: J. Preželj), Division of Internal Medicine, University Medical Center, Ljubljana
August 1, 1996 – September 30, 1996 Postgraduate Year-1 Resident, Division of Surgical Oncology (Mentor: M. Auersperg), Institute of Oncology, Ljubljana
March 11, 1996 – June 12, 1996 Postdoctoral Researcher, Medical Teaching Facilities, Department of Neurosciences (Mentor: T. Saitoh), School of Medicine, University of California San Diego, La Jolla, California, USA
October 1, 1995 – March 8, 1996 Postgraduate Year-1 Resident, Department of Cardiovascular Surgery, Division of Surgery (Mentor: N. Kovačič), University Medical Center, Ljubljana
July 10, 1995 – September 29, 1995 General physician, 2 Primary Health Care Centers Lucija and Koper at locations in Lucija and Šmarje pri Kopru and at the Home for the Elderly Markovec in Koper, Lucija and Koper
January 16, 1995 – May 19, 1995 Medical Intern, Primary Health Care Center Piran (Mentor: O. Šinkovec) at locations in Piran and Sečovlje, Piran and Sečovlje
January 3, 1995 – May 19, 1995 Medical Intern – Volunteer, Departments of Ear, Neck and Throat and General Surgery (Mentor: N. Kinkela), General Hospital, Izola
April 1, 1994 – September 30, 1994 Medical Intern (Mentors: L. Peratoner, M. Russolo and C. Scarpa), Departments of Internal Medicine, Obstetrics and Gynecology and Surgery, Cattinara and Burlo Garofolo, School of Medicine, University of Triest, Triest, Italy
September 3, 1990 – September 28, 1990 Medical Student – Volunteer, Department of Surgery (Mentor: F. Rivoalon), Hotel-Dieu, Lyon, France
October 5, 1987 – March 8, 1994 Medical Student, School of Medicine (Mentors: A. Bosatra then M. Russolo), University of Triest, Triest, Italy
July 1, 1986 – July 27, 1987 Consultant for East African Affairs, Research Center for Cooperation with Developing Countries (Supervisor: B. Hvastija), Ljubljana, Slovenia and Nairobi, Kenya.

EDUCATION
January 16, 2011 Advocate Class of the 2011 Donald M. Palatucci Advocacy Leadership Forum graduation, American Academy of Neurology, St. Paul, Minnesota, USA
June 17, 2010 Board Certification in Neurology – Summa Cum Laude (Mentor: D.B. Vodušek), Medical Chamber of Slovenia, Ljubljana
July 14, 2003 Doctor of Philosophy in Neurosciences (Mentor: L.S.B. Goldstein; diploma nostrified in Slovenia on February 5, 2006), Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, California, USA
Doctoral Thesis: Probing for axonal defects in Alzheimer’s disease (F.E. Bloom, D.W. Cleveland, M.G. Farquhar, F.H. Gage and L.S.B. Goldstein, Chair), December 11, 1998 Master of Sciences in Neurosciences (Mentor: G. Schulteis), Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, California, USA
Master Thesis: Urocortin: A satiety factor? (P.L. Mellon, P.E. Sawchenko, G. Schulteis, Chair and W.W. Vale), March 8, 1994 Medical Doctor (Final score: 110/110, diploma nostrified in Slovenia on October 25, 1994), School of Medicine, University of Trieste, Trieste, Italy
Doctoral Thesis: Reconstruction of the mandible (Mentor: M. Russolo, Co-mentor: Z.M. Arnež), June 26, 1987 University of Cambridge Advanced Level Certificate of Education, Hillcrest Secondary School, Nairobi, Kenya
Subjects: Mathematics and biology (Mentors: G. Duffield, P.B. Gunter)

PROFESSIONAL SOCIETIES
2009 – 2010 British Medical Council.
2009 – now American Academy of Neurology.
2007 – now SiNAPSA – Slovene Neuroscience Association.
2005 – 2008 American Association for the Advancement of Science.
2005 – now Slovenian Chapter of the European Confederation of Neuropathological Societies.
2004 – now Slovenian Chapter of the European Federation of Neurological Societies.
2004 – now Society for Neuroscience.
1998 – 2000 Mitochondrial Medicine Society.
1998 – now University of California San Diego Alumni.
1998 – now Boehringer-Ingelheim Fonds Alumni.
1995 – now Slovene Medical Society.
1994 – now Medical Chamber of Slovenia.
1987 – now Hillcrest Secondary School Alumni.

BRIEF SUMMARY OF RESEARCH INTERESTS
The overall goal of my research is to further our knowledge about diseases that cause dementia with particular emphasis on Alzheimer’s di­sease. To achieve this goal I perform basic as well as clinical research. From the basic science prospective, my research focuses on identifying mechanisms that underlie early structural changes observed in brains afflicted by Alzheimer’s and related neurodegenerative diseases. More specifically, the major questions I’m addressing are: 1) what are the earliest identifiable pathological changes, 2) what are the mechanisms responsible for these early pathological changes and 3) how do these early changes relate to the well-established pathological lesions as well as clinical phenotypes observed in Alzheimer’s and related neurodegenerative diseases? Since my work to date identified axons as an early site of damage in Alzheimer’s and related neurodegenerative diseases particular effort is made to uncover those aspects of the biology of the axons that may be implicated in the development of pathology. Answers to these questions should broaden our understanding of brain physiology and improve diagnostics and therapeutics of the dementias. Clinically, the research focuses on identifying and explaining those early cognitive and behavioral changes in subjects afflicted by Alzheimer’s and related neurodegenerative disorders that may be of diagnostic relevance. Effort is made to correlate clinical changes with pathological findings.

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